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In the landmark 2017 study, FOXO4-DRI selectively induced apoptosis in senescent human fibroblasts (IMR90 cell line) while sparing non-senescent cells at an 11.73-fold selectivity ratio

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Contraindicaciones: De acuerdo con todas las investigaciones realizadas hasta el momento, no se conoce ninguna interaccin negativa con ningn medicamento

Talk to a doctor if weight loss feels too fast, appetite becomes too low, or you notice weakness, dizziness, dehydration, vomiting, constipation, or low blood sugar symptoms

Large randomized controlled trials in humans are absent, so clinical efficacy claims lack robust evidence